بررسی میزان جذب فومونیزین B1 توسط نانوذرات سلولز اصلاح شده با پلی لیزین در حضور مواد غذایی مختلف

Introduction: Fumonisin B1 is a mycotoxin which can lead to neural defects, esophageal cancer, liver and kidney diseases. The aim of this study was to investigate the ability of nanocellulose conjugated with poly-lysine to remove fumonisin B1 in the different foodstuffs. Methods: First, nanocellulose was synthesized by acid hydrolysis, modified by citric acid, and conjugated with poly-lysine by cross-linker. In the next step, four foodstuffs including wheat flour, maize flour, rice flour, and cucumber were prepared, and serial concentrations of fumonisin B1 were added to them. Then, conjugated nanocellulose (2000 µg/mL) was separately added to each tube, and after incubation, the exact concentration of toxin in each tube was analyzed by HPLC. Finally, the percentage of adsorption for each tube was calculated, according to control. Results: This study revealed that although the nanoparticles could adsorb fumonisin B1 in the all foodstuffs, but the highest adsorption (95%) was seen for cucumber. Also, results showed that there is direct relation between the percentage of adsorption and the initial concentration of fumonisin B1. Conclusions: In this study, for the first time, nanocellulose conjugated with poly-lysine was introduced as fumonisin B1 adsorbent, and may be used for removal of the toxin in the various foodstuffs.